/ en /research-abstracts/step-regenerative-injection-therapy-severe-chronic-low-back-pain-utilizing <!-- THEME DEBUG --> <!-- THEME HOOK: 'field' --> <!-- FILE NAME SUGGESTIONS: * field--node--title--research-abstract.html.twig x field--node--title.html.twig * field--node--research-abstract.html.twig * field--title.html.twig * field--string.html.twig * field.html.twig --> <!-- BEGIN OUTPUT from 'core/modules/node/templates/field--node--title.html.twig' --> <span>Step-Up Regenerative Injection Therapy for Severe Chronic Low Back Pain Utilizing Epidural Dextrose Solution (Prolotherapy), Local Platelet-Rich Plasma, and Epidural Platelet-Rich Plasma: A Case Report and Suggested Protocol</span> <!-- END OUTPUT from 'core/modules/node/templates/field--node--title.html.twig' --> <!-- THEME DEBUG --> <!-- THEME HOOK: 'field' --> <!-- FILE NAME SUGGESTIONS: * field--node--uid--research-abstract.html.twig x field--node--uid.html.twig * field--node--research-abstract.html.twig * field--uid.html.twig * field--entity-reference.html.twig * field.html.twig --> <!-- BEGIN OUTPUT from 'core/modules/node/templates/field--node--uid.html.twig' --> <span> <!-- THEME DEBUG --> <!-- THEME HOOK: 'username' --> <!-- BEGIN OUTPUT from 'core/modules/user/templates/username.html.twig' --> <span lang="" about="/user-profile/sana" typeof="schema:Person" property="schema:name" datatype="">sana</span> <!-- END OUTPUT from 'core/modules/user/templates/username.html.twig' --> </span> <!-- END OUTPUT from 'core/modules/node/templates/field--node--uid.html.twig' --> <!-- THEME DEBUG --> <!-- THEME HOOK: 'field' --> <!-- FILE NAME SUGGESTIONS: * field--node--created--research-abstract.html.twig x field--node--created.html.twig * field--node--research-abstract.html.twig * field--created.html.twig * field.html.twig --> <!-- BEGIN OUTPUT from 'core/modules/node/templates/field--node--created.html.twig' --> <span>Wed, 04/30/2025 - 11:39</span> <!-- END OUTPUT from 'core/modules/node/templates/field--node--created.html.twig' --> <!-- THEME DEBUG --> <!-- THEME HOOK: 'links__node' --> <!-- FILE NAME SUGGESTIONS: * links--node.html.twig x links.html.twig --> <!-- BEGIN OUTPUT from 'themes/bootstrap/templates/system/links.html.twig' --> <!-- END OUTPUT from 'themes/bootstrap/templates/system/links.html.twig' --> <!-- THEME DEBUG --> <!-- THEME HOOK: 'field' --> <!-- FILE NAME SUGGESTIONS: * field--node--body--research-abstract.html.twig * field--node--body.html.twig * field--node--research-abstract.html.twig * field--body.html.twig * field--text-with-summary.html.twig x field.html.twig --> <!-- BEGIN OUTPUT from 'themes/pivot/templates/field.html.twig' --> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><h3>Abstract</h3> <p>Chronic low back pain (CLBP) is a prevalent problem that rarely resolves completely and frequently has a negative impact on mood, activity, and mobility. Conservative pharmacologic and non-pharmacologic therapies have limited efficacy, and there is an unmet therapeutic need for these patients. The authors report a case of a 38-year-old male patient with a 6-year history of moderate to severe back pain, significantly impaired mobility and neurologic deficits that were resistant to a wide range of conservative therapies. Physical exam and magnetic resonance imaging (MRI) revealed evidence of radiculopathy, with impaired sensation and strength that was consistent with a right L5 nerve root impingement. Repeated caudal epidural injection of dextrose solution caused rapid, though not durable, improvement in symptoms and mobility, with some effect on neurologic findings. Stepping up to caudal epidural platelet-rich plasma (PRP) injection combined with articular PRP injections at the sacroiliac joint and lumbar facet joints resulted in almost complete resolution of pain, marked improvements in mobility and resumption of physical activity. Also, after caudal epidural PRP injection the patient regained sensation and function over the right L5 distribution for the first time in 6 years. The injections were well tolerated, and the patient was very pleased with the therapy. The case report also includes a brief review of and suggested approach to injection therapy for the naturopathic physician treating resistant CLBP.</p> <p>DOI link: <a href="https://doi.org/10.54434/candj.198" target="_blank"> https://doi.org/10.54434/candj.198</a></p> <p> </p> </div> <!-- END OUTPUT from 'themes/pivot/templates/field.html.twig' --> <!-- THEME DEBUG --> <!-- THEME HOOK: 'field' --> <!-- FILE NAME SUGGESTIONS: * field--node--field-author--research-abstract.html.twig * field--node--field-author.html.twig * field--node--research-abstract.html.twig * field--field-author.html.twig * field--text.html.twig x field.html.twig --> <!-- BEGIN OUTPUT from 'themes/pivot/templates/field.html.twig' --> <div class="field field--name-field-author field--type-text field--label-above"> <div class="field--label">Author</div> <div class="field--item"><p>Jessica Hobson, Andrew Vargo</p> </div> </div> <!-- END OUTPUT from 'themes/pivot/templates/field.html.twig' --> <!-- THEME DEBUG --> <!-- THEME HOOK: 'field' --> <!-- FILE NAME SUGGESTIONS: * field--node--field-date--research-abstract.html.twig * field--node--field-date.html.twig * field--node--research-abstract.html.twig * field--field-date.html.twig * field--datetime.html.twig x field.html.twig --> <!-- BEGIN OUTPUT from 'themes/pivot/templates/field.html.twig' --> <div class="field field--name-field-date field--type-datetime field--label-above"> <div class="field--label">Citedate</div> <div class="field--item"> <!-- THEME DEBUG --> <!-- THEME HOOK: 'time' --> <!-- BEGIN OUTPUT from 'core/modules/system/templates/time.html.twig' --> <time datetime="2025-03-20T12:00:00Z">2025-03-20</time> <!-- END OUTPUT from 'core/modules/system/templates/time.html.twig' --> </div> </div> <!-- END OUTPUT from 'themes/pivot/templates/field.html.twig' --> <!-- THEME DEBUG --> <!-- THEME HOOK: 'field' --> <!-- FILE NAME SUGGESTIONS: * field--node--field-research-abs-citation--research-abstract.html.twig * field--node--field-research-abs-citation.html.twig * field--node--research-abstract.html.twig * field--field-research-abs-citation.html.twig * field--text.html.twig x field.html.twig --> <!-- BEGIN OUTPUT from 'themes/pivot/templates/field.html.twig' --> <div class="field field--name-field-research-abs-citation field--type-text field--label-above"> <div class="field--label">Citation</div> <div class="field--item"><p>Hobson J, Vargo A. Step-Up Regenerative Injection Therapy for Severe Chronic Low Back Pain Utilizing Epidural Dextrose Solution (Prolotherapy), Local Platelet-Rich Plasma, and Epidural Platelet-Rich Plasma: A Case Report and Suggested Protocol.</p> </div> </div> <!-- END OUTPUT from 'themes/pivot/templates/field.html.twig' --> <!-- THEME DEBUG --> <!-- THEME HOOK: 'field' --> <!-- FILE NAME SUGGESTIONS: * field--node--field-research-abs-publication--research-abstract.html.twig * field--node--field-research-abs-publication.html.twig * field--node--research-abstract.html.twig * field--field-research-abs-publication.html.twig * field--text.html.twig x field.html.twig --> <!-- BEGIN OUTPUT from 'themes/pivot/templates/field.html.twig' --> <div class="field field--name-field-research-abs-publication field--type-text field--label-above"> <div class="field--label">Publication</div> <div class="field--item"><p>CAND Journal</p> </div> </div> <!-- END OUTPUT from 'themes/pivot/templates/field.html.twig' --> <!-- THEME DEBUG --> <!-- THEME HOOK: 'field' --> <!-- FILE NAME SUGGESTIONS: * field--node--field-taxonomy--research-abstract.html.twig * field--node--field-taxonomy.html.twig * field--node--research-abstract.html.twig * field--field-taxonomy.html.twig * field--entity-reference.html.twig x field.html.twig --> <!-- BEGIN OUTPUT from 'themes/pivot/templates/field.html.twig' --> <div class="field field--name-field-taxonomy field--type-entity-reference field--label-above"> <div class="field--label">Taxonomy</div> <div class="field__items"> <div class="field--item"><a href="/research-abstracts/chronic-pain" hreflang="en">Chronic Pain</a></div> </div> </div> <!-- END OUTPUT from 'themes/pivot/templates/field.html.twig' --> Wed, 30 Apr 2025 15:39:01 +0000 sana 4846 at