Abstracts

Vitamin C for the Treatment of Depression in Cancer Patients: A Literature Review

Introduction

One in two Canadians will be diagnosed with cancer in their lifetime and one in four will experience depression during their diagnosis. The cause of depression during cancer could be related to psychological, social, inflammatory, or immunological factors. Vitamin C can exert an effect on oxidative stress levels, adrenal function, and immune function and may have a role in the treatment of both cancer and depression.

Title of abstract:
Vitamin C for the Treatment of Depression in Cancer Patients: A Literature Review
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Abstracts

Exploring the Effects of Yoga Therapy on Heart Rate Variability and Patient-Reported Outcomes After Cancer Treatment: A Study Protocol

Background:

Following cancer treatment, adults commonly report worsened patient-reported outcomes (PROs) such as anxiety, stress, depression, persistent and upsetting cognitive complaints, unrelenting fatigue, and reduced quality of life. Poorer PROs are associated with disrupted autonomic nervous system functioning as measured by heart rate variability (HRV), both of which have been associated with greater morbidity and mortality. Interventions to improve HRV and PROs among adults following cancer treatment are needed.

Title of abstract:
Exploring the Effects of Yoga Therapy on Heart Rate Variability and Patient-Reported Outcomes After Cancer Treatment: A Study Protocol
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Abstracts

Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis.

Most observational studies show an association between melatonin and cancer in humans. We conducted a systematic review of randomized controlled trials (RCTs) of melatonin in solid tumor cancer patients and its effect on survival at 1 yr. With the aid of an information specialist, we searched 10 electronic databases from inception to October 2004. We included trials using melatonin as either sole treatment or as adjunct treatment. Pre-specified criteria guided our assessment of trial quality. We conducted a meta-analysis using a random effects model.

Title of abstract:
Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis.
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Abstracts

The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review.

BACKGROUND: Green tea is widely used by women for the prevention and treatment of breast cancer. The authors aimed to determine the efficacy of green tea ingestion on the risk of breast cancer development and the risk of breast cancer recurrence. METHODS: The authors conducted a systematic review and meta-analyses of observational studies from systematic searches of 8 electronic data sources and contact with authors. They included studies assessing breast cancer incidence and recurrence.

Title of abstract:
The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review.
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Abstracts

An in vivo analysis of the herbal compound Essiac.

BACKGROUND: Essiac is a herbal compound that has been in common use with cancer patients in North America for over 80 years. Despite its relatively widespread use, there are no peer-reviewed published reports of in vivo studies regarding the use of this compound.MATERIALS AND METHODS: Essiac was administered orally to test animals prior to all experiments. Standard assays to test protection from ethanol-induced gastric ulceration and carbon tetrachloride-induced hepatic injury were performed on Wistar rats.

Title of abstract:
An in vivo analysis of the herbal compound Essiac.
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Abstracts

Metronomic dosing of chemotherapy: applications in pediatric oncology.

Pediatric cancer has a better outcome profile than adult cancers. However, refractory disease and the potential for long-term morbidity resulting from the use of conventional therapies necessitate the development of novel treatments for this population. Recent advances in oncology include the use of low dose metronomic (LDM) chemotherapy. The promise of this novel therapeutic approach includes reduced toxicity and the potential for efficacy predominantly through an antiangiogenic effect.

Title of abstract:
Metronomic dosing of chemotherapy: applications in pediatric oncology.
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Abstracts

Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors.

BACKGROUND: Enrolling participants onto clinical trials of cancer presents an important challenge. We aimed to identify the concerns of patients with cancer about, and the barriers to, participation in clinical trials.METHODS: We did a systematic review to assess studies of barriers to participation in experimental trials and randomized trials for validity and content.

Title of abstract:
Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors.
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Abstracts

In vitro analysis of the herbal compound Essiac.

BACKGROUND: Despite the recommendation of the Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative, little research has been published on the widely used herbal compound Essiac. We aimed to address this deficiency by conducting a series of assays to determine some of the purported activities of Essiac in vitro.

Title of abstract:
In vitro analysis of the herbal compound Essiac.
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Abstracts

Patient decision-making about complementary and alternative medicine in cancer.

OBJECTIVE: In this paper, we set out to describe the personal and social contexts of treatment decisions made by cancer patients concerning complementary and alternative medicine (cam) and also the process through which cancer patients reach cam decisions throughout the cancer trajectory. METHODS: We selected and reviewed a variety of cam decision-making models published in the past 10 years within the Canadian health literature. RESULTS: The cam decision-making process is influenced by a variety of sociodemographic, disease-related, psychological, and social factors.

Title of abstract:
Patient decision-making about complementary and alternative medicine in cancer.
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Abstracts

Integrative practices of Canadian oncology health professionals.

OBJECTIVE: Cancer patients are increasingly known to use complementary medicine (cam) during conventional treatment, but data are limited on how Canadian oncology health professionals attempt to assist patients with their use of cam in the context of conventional cancer care. As part of a larger qualitative study assessing the perceptions of Canadian oncology health professionals regarding integrated breast cancer care, we undertook an exploration of current integrative practices of oncology health professionals.

Title of abstract:
Integrative practices of Canadian oncology health professionals.
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